Building upon the foundational knowledge and insights in AIML901-MORS, this course examines opportunities in business where AI intersects with organizational behavior, leadership, and business strategy. The goal of the course is to equip future leaders with the frameworks to identify and evaluate AI opportunities, manage AI-driven products, navigate ethical dilemmas, and lead teams of both human and machine intelligence. We will explore a wide range of business applications emerging from the capabilities and limitations of AI systems including ChatGPT, Gemini, Claude, IBM Watson, Netflix and Tiktok’s recommender systems, and AI systems for recognizing and responding to emotion. This course is an interactive lecture and case-based course with one individual assignment, one quiz, and a final group project that have both individual and group elements. This course is based on the second five weeks of Professor Groh’s 2024 and 2025 Human and Machine Intelligence MORS950 course, and it’s continually updated with the latest science and industry insights. Past guest speakers include product managers at OpenAI, Deepmind, Anthropic, Mindtrip, Paypal, and Spotify. By the end, you should be an expert at identifying promising business use-cases of frontier AI technologies and evaluating AI’s current limitations such that you can apply human and machine thought partnerships to grow new businesses and disrupt Grand Masters in any field.